Which of the following statements is true about pesticide application?

The correct statement regarding pesticide application is that label instructions must always be followed during application. The pesticide label serves as the legal guideline for the safe and effective use of the product. It provides critical information about how to apply the pesticide, including the correct dosage, application techniques, and timing. Following these instructions is essential not only for the effectiveness of the treatment but also for the safety of the applicator, the public, and the environment.

Adhering to label instructions helps prevent misuse, which can lead to ineffective pest control and potential harm to non-target organisms, including beneficial insects and wildlife. In contrast, the other statements provide misconceptions: not all pesticides can be applied at any time due to various factors such as environmental conditions; careful application is necessary for all types of pesticides, not just systemic ones; and mixing pesticides requires knowledge and caution to avoid harmful reactions or reduced effectiveness.